I would not be able to manage without my daily pillbox. Just too ez to 4get things without it, then later wondering if took something or not. But that doesn't always mean I remember...
2 years ago I had to transition from normal life where I took my warfarin after coming home from work (or after dinner on days off), to an upside down inside out 12 hour timeshifted backwards nightshift from hell. To keep the warfarin meds on roughly same daily time as b4 I did NOT shift 12 hours fwds or back I just started taking it when I got up which was then in the evening. Which was a very ez adjustment to make though, get up, take the pills.
Now I am back to "normal" lifestyle with dayshift again (HALLELUJAH! Can't believe I lasted 2 years in the godawful hell) and to keep warfarin on same 24 hour clock I have to go back to taking it after work/dinner again and finding it difficult to remember even with the pillbox since I got used to just taking the pills upon waking up. Have had to put up NOTES around the house to remind me to take it in the evening now despite the pills being in the PM part of my pillbox, until I do it enough such that that part of my brain associated with performing non-thinking automatic tasks gets trained for this schedule again.