Since warfarin is a slower-metabolizing drug than many others, taking up to 48-72 hours for a dosage to show its full effect, it's not going to hurt to compensate forgotten doses this way. And I did run it past my PCP and my cardio.
If you're only upping a dose by 2mg and he takes 8.5 daily, then he's still down 6.5 for the week -- if I follow your train of thought. The larger the dose you take, the more of a nosedive you take when you don't take your usual dose. For example, a person who only takes 3mg daily won't see a significant nosedive in his/her INR if a dose is dropped.
I take 5mg Tu-Th-Sat-Sun and 5.5 on M-W-F. I recently forgot a 5.5mg dose -- noticed it the next day. So I took 5mg + 3mg that day, for a total of 8mg. The next day I took my usual 5.5 + the remaining 2.5mg, for a total of 8mg. My INR may go up slightly temporarily, but I'd rather that than have it drop, since it's in the mitral position.
