The reason for being on warfarin is that clots can build up on mechanical valves, with the potential to break off and cause stroke. If it weren't for that, none of us would be on the stuff! Higher warfarin doses lead to higher INR, which translates into less clotting and lower stroke risk. INR itself is "international normalized ratio" and is an objective comparison of an individual's clotting time compared to "normal"; an INR of 2, for example, means your clotting time is twice the normal time. If INR is too low, the risk of stroke goes up. Likewise, there are risks inherent in INR's that are too high (spontaneous bleeds or dangerously slow clotting with wounds or potentially with concussions/head injury). A couple of the members here have posted links to long-term research that indicates that the risks from too low an INR are significantly greater than those from INR being too high, which is why people here are stressing that there isn't really that much to be gained by a slightly lower INR, but potentially much more risk. Hope that little primer helps!What are the risks. I don’t understand INR . Why would a low INR cause a stroke? I’m trying to learn and really appreciate all of your advice. This is happening so fast and I’m trying to make the right decisions and be as informed as I can be.
Even in Europe, ON-X manufacturer does not indicate as you believe you heard:My cardiologist said in Europe they only take An aspirin a day with an on X valve and are not required to take warfarin. I believe that’s what he said anyway. A lot was said and I’m still sifting through everything in my mind.
I didn't cite it here because the question was about the On-X and I don't think the On-X is included in that study...
it may have been what he said but the reality is (even if he didn't know it) that you MUST take the Aspirin AND take the Warfarin AND keep your INR strictly above the minimum in that range.My cardiologist said in Europe they only take An aspirin a day with an on X valve and are not required to take warfarin. I believe that’s what he said anyway.
nice ... love the wording ... exactly the wording made by Dr Schaff in his presentation ... that its their valve that does this, not the ACT ;-)Even in Europe, ON-X manufacturer does not indicate as you believe you heard:
Well, is a good peace if mind to know that in the event of your INR going below 2 you are safe, mine at the begining went on for 1.5 to 1.9 for weeks, and all went fine. Now after 4 years, i just keep it above 2, so IF it goes down in one of travels to other countries/places, i know for a fact that at 1.6 it works fine, BUT, yes, i do try to keep it at 2.2, and if it goes to 2.5 if fine, and if it goes to 1.6 is fine too, that is how it works " for me", we all have different realms of thoughtThanks everyone for all the great advice. I thought with the on X valve that your INR would be more in 1.5 to 2.0 range. It seems that all of you are more in the 2 to 3 range. Why all the literature and ad campaigns touting a lower INR if nobody is in those ranges??
Using 1 mg as my second pill allows me to adjust the number of days I need to take 7 mg quite easily. Sometimes I need just one more or less mg per week. Very easy to do with 5’s and 1’s on hand.Superman: If your dose alternates between 6 mg one day and 7 mg the next, why don't you just take 6.5? (Yeah - I think I know the answer - it's harder to get a dose of 6.5 than it is to get 6 or 7 - but the answer may be as easy as taking one 4 mg and one 2.5 mg pill per day).
I have a St. Jude valve. The range recommended is 2-2.5. That's what I keep it at by testing every 2-3 weeks. I take warfarin and aspirin as directed. The range comes from two personal cardiologist and at least 3 others within the practice's Coumadin Clinic. Since I occasionally get a bleeding hemorrhoid I have a good reason to not keep my INR higher than needed. I also can get nose bleeds In addition, I had a surgery where my recovery time was longer due to extra bleeding caused by my higher than normal INR.Thanks everyone for all the great advice. I thought with the on X valve that your INR would be more in 1.5 to 2.0 range. It seems that all of you are more in the 2 to 3 range. Why all the literature and ad campaigns touting a lower INR if nobody is in those ranges??