Erythromycin + warfarin
- Thread starter steve119
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Lisa in Katy
I can't remember if I've been on E-mycin, but I do know that every antibiotic I have ever taken has affected my INR. Always on the high end.
Ross
Well-known member
Check your INR in 3 days. It's going to rise, but how much is the question. For future reference when you need to check interactions, copy this link to your favorites:
http://www.drugdigest.org/DD/Interaction/ChooseDrugs/1,4109,,00.html
WARFARIN SODIUM (in Coumadin) may interact with ERYTHROMYCIN (in Erythromycin Tablets, Capsules, and Extended-Release)
Erythromycin may block the breakdown of warfarin by the liver. If this happens, blood levels of warfarin could be increased and this could increase its anticoagulant effect. Warfarin is generally used to prevent your blood from "coagulating" or forming blood clots. When erythromycin and warfarin are used at the same time, your blood may be much less likely to clot and this may increase the risk of excessive bleeding. If these drugs are taken together, your doctor may want to monitor you closely when therapy with erythromycin is either started or stopped. Blood tests can be used to make sure that you are getting the right amount of warfarin. If you are experiencing problems, it may be necessary to adjust the dose of warfarin. Ask your healthcare provider about these drugs and this potential interaction as soon as possible.
This interaction is well-documented and is considered major in severity.
http://www.drugdigest.org/DD/Interaction/ChooseDrugs/1,4109,,00.html
WARFARIN SODIUM (in Coumadin) may interact with ERYTHROMYCIN (in Erythromycin Tablets, Capsules, and Extended-Release)
Erythromycin may block the breakdown of warfarin by the liver. If this happens, blood levels of warfarin could be increased and this could increase its anticoagulant effect. Warfarin is generally used to prevent your blood from "coagulating" or forming blood clots. When erythromycin and warfarin are used at the same time, your blood may be much less likely to clot and this may increase the risk of excessive bleeding. If these drugs are taken together, your doctor may want to monitor you closely when therapy with erythromycin is either started or stopped. Blood tests can be used to make sure that you are getting the right amount of warfarin. If you are experiencing problems, it may be necessary to adjust the dose of warfarin. Ask your healthcare provider about these drugs and this potential interaction as soon as possible.
This interaction is well-documented and is considered major in severity.
