I don't see anything that would toy with INR.
INGREDIENTS
Plant sterols/stanols
Other Ingredients: Tricalcium Phosphate, Croscarmellose Sodium, Hydroxypropyl Methylcellulose, Calcium Carbonate, Silicon Dioxide, Stearic Acid, Magnesium Stearate, Titanium Dioxide (artificial color), Polyethylene Glycol, Triethyl Citrate, Polysorbate 80, Sodium Citrate.
PRECAUTIONS
Not for use by pregnant or lactating women or young children. Check with your physician before beginning use of CholestOff if you are currently using medications to lower your cholesterol. Keep bottle tightly closed. Store in a cool, dry place out of reach of children. Do not use if imprinted seal under cap is broken or missing. Color variation is normal with this natural product.
†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.