INRatio 0.6 INR low ?

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Marty

Marty

Well-known member
Joined
Jun 10, 2001
Messages
1,597
Location
McLean, VA
I had a muscle compartment bleed in my leg a couple of years ago after a hard fall on the golf course ( dangerous game, particularly if you don't look where you are going!). Completely recovered but I did cut back on the warfarin on advice of my doctor, running the INR close to 2.5. Lately I've upped it to 3.5-4.0 where I used to keep it. My question is: Is it still believed by our group that the INRatio tests about .6 INR high or low compared to a central lab monitor? For a while there was comment that in simultaneous tests with central labs and Coagucheks the INRatio always came outhigh-about .6. Any thoughts ,fellow INRatio users?
 
It is still my experience that it runs about .4 low. Recently during my hospital stay, my INR came back at 3.2 and I was testing around 3.6 with the INRatio.

Granted it was not a simulaneous test (about 24 hours apart) but past lab comparisons turned out about the same.
 
Some of us have thought so. I don't have a lab test to compare to. But we've also had members post that there's was just about spot-on with labs or other machines.
 
It once worked that way for me Marty, but there is no substance to it. Last time with my GI bleed, I was .2 different from the lab. I'd say believe the machine.
 
.2 no more or less is where my MDs prefers (if there is a dif) between the lab and home test. My Coaguchek had always been on the mark. Should have my new INratio sometime in Jan. Will do a comparsion and report my numbers:)
 
.2 seems like a pretty stiff difference to hold to, considering that we're told that lab tests run on the same tube of blood can have a .5 difference.
 
Thanks, my friends. I will believe the INRatio INR and not make adjustments.
 
Hemosense says that there can be up to a .6 difference and I used to see exactly that, but not in the last two boxes of new strips. It's been pretty much dead on.
 
I've found that the INRatio routinely reads about 20% low (about the 0.6 in the INR 3.0 range, more with a reading of 4.0) Whether the lab or the tester is right, I set up the INRatio to a 3.0-4.0 range, and get less grief from the Cardio as the labs are in the 2.5-3.5 range. He prefers I aim for the upper end of the range, so he's OK with my self testing and dosing. I've had so much doctoring, that if I can stay away from doctors and lab techs, I'll be better off.
My communications with Hemosense put this within range, but I've never heard any stories of it being lower than the lab tests. Then again, who says the local lab's result is the "gold standard" anyway?
 
Greetings folks!

Please use caution when advising others on INRatio performance. As everyone should be working with their physician to decide how to respond to the readings on their monitor.

I'll direct you to the following tech bulletin from HemoSense.

http://www.hemosense.com/docs/5500258_TechBull103_INR_ISI_revB.pdf

Note: the graph on the second page shows results comparting various LAB INSTRUMENTS using the same samples.

My advice is to always compare your monitor to the same reference device your physician uses. Work off that data and not how other INRatio users state that their INRatio compare to their physician's reference device.
 
Ross, curious. With the two new batches of strips. Did you have a lab comparsion as well?

In any case....we are all aware that home testing is a MAJOR advantage. Either method, lab - home. Varitations will occur. I beleive more so at the lab. There is less contol and more room for error!
 
HemoSense-Brendan said:
Greetings folks!

Please use caution when advising others on INRatio performance. As everyone should be working with their physician to decide how to respond to the readings on their monitor.

I'll direct you to the following tech bulletin from HemoSense.

http://www.hemosense.com/docs/5500258_TechBull103_INR_ISI_revB.pdf

Note: the graph on the second page shows results comparting various LAB INSTRUMENTS using the same samples.

My advice is to always compare your monitor to the same reference device your physician uses. Work off that data and not how other INRatio users state that their INRatio compare to their physician's reference device.
Click to expand...
Aye Aye Captain! :)
 
LUVMyBirman said:
Ross, curious. With the two new batches of strips. Did you have a lab comparsion as well?

In any case....we are all aware that home testing is a MAJOR advantage. Either method, lab - home. Varitations will occur. I beleive more so at the lab. There is less contol and more room for error!
Click to expand...
Yeap, hospital lab. Of course, the ER Doc was concerned about my HIGH INR of 3.2. :rolleyes:
 
For Brendan

For Brendan

HemoSense-Brendan said:
Greetings folks!

Please use caution when advising others on INRatio performance. As everyone should be working with their physician to decide how to respond to the readings on their monitor.

I'll direct you to the following tech bulletin from HemoSense.

http://www.hemosense.com/docs/5500258_TechBull103_INR_ISI_revB.pdf

Note: the graph on the second page shows results comparting various LAB INSTRUMENTS using the same samples.

My advice is to always compare your monitor to the same reference device your physician uses. Work off that data and not how other INRatio users state that their INRatio compare to their physician's reference device.
Click to expand...

That's my question. isi,INR normalizes all results for variations in thromboplastin sensitivity. THE MONITORS VARY. Does the hemosense INRratio monitor report @ INR 0.6HIGH OR LOWcompared to a central lab monitor? Has Hemosense ever studied this?I check my monitor against my central lab once a year. The central lab uses a CA-1000 with DADE Inovin thromboplastin. Last year my INRatio gave me 3.6INR and the lab gave 2.3INR I told my doctor this was an expected variation and that I would try to get my INRatio reading up around 4 which would probably be a central lab 3.3 or 3.4. Does this make sense, Brendan?
 
LUVMyBirman said:
Was that a joke Ross? LOL:p ;)
Click to expand...
No hon, he really thought 3.2 was high. I argued with him about it. I said, "yes, high in range" and he didn't accept that. I told him to call my cardiologist and ask him.
 
Did you hear the one about the ER doc that thought the patient had an enlarged heart? When prior to surgery she did not? Well, the ER doc says.......you know must be aware your heart in enlarged...you just had OHS. Turns out she had cardiac tamponade:eek:

I have to joke about this now. At the time it wasn't funny.
 
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