New mechanical valve - no warfarin

[Valve-Viking]

On the 23rd of october a new mechanical valve designed and researched at the "Karolinska" University Hospital, Stockholm, Sweden, was implanted in the first human receiver. This was the first out of 5 planned human replacals.

The mechanical valve is said to have a new design which do not require any warfarin-treatment at all. It is also noise-free(no clicking).

The valve has been tested equivalent to 20 years use without warfarin
succesfully.

I will follow this with great interest - will let you all know if anything further.

/
Martin

 

[geebee]

Martin,

Sounds interesting. I wonder what happens after 20 years tho?

Will look forward to any updates.

 

[Valve-Viking]

Gina,

Who knows what will happen, but I guess the results are encourageing and safe enough to proceed with human trials. Everything has to have a start,
let´s hope they are on to something. The medical authorities are very strict,
so do not think they´d be allowed to go human without good chances.


/
Martin

 

[Oslo73]

Interested!

Interested!

Does this valve have a name?
Might help the google search!

 

[Valve-Viking]

Hi Olso 73,

Don´t know the name, it never said, but if you are Norwegian, you can google "hjärtklaff + karolinska" and you will find information from different Swedish media-sources. It was on the main news a few days ago, I only had time to write here just now.

Ha det!

/
Martin

 

[Oslo73]

Light on the horizon

Light on the horizon

Hi Olso 73,

Don´t know the name, it never said, but if you are Norwegian, you can google "hjärtklaff + karolinska" and you will find information from different Swedish media-sources. It was on the main news a few days ago, I only had time to write here just now.

Ha det!

/
Martin

I found a video. Unfortunately it is in Swedish, so all you non Scandinavians out there won`t find it that interesting. You get to see the valve, which was interesting though. It has three leaflets in what looked like bright metal of some kind. My guess is titanium.
Try this page and you can see a small picture of it.
http://aftonbladet.se/vss/halsa/story/0,2789,916479,00.html

 

[LUVMyBirman]

Wonder what position it was implanted in? My guess would be aortic.

This is one alternative I am banking on for my Mechanical re-do down the road. My card said I should expect 25-30 years from my exsisting valve. Meaning I have 15-20 before I need to be concerned with it. By then....hoping for some great new "tested" technology!

 

[RCB]

"New"?

"New"?

Looks like the old Tri-Flow valve mention here a few years ago. My first valve
was a tri-leaflet design. Just goes to show "What's old, is new again!"

Send this to Dr. Pettersson at CCF, he is a Swed.

 

[catwoman]

RCB:

Great to see a post from you!! Long time, no see...

 

[Rush20]

Sort of reminds of gradeschool dares..."No, you go first."

Hopefully this is indeed the new wave of the future.

 

[Farid]

I believe that is the valve in question..........
http://www.ki.se/medicin/medicine_ks/cardiology_unit/research/valve&refr.html

 

[chrisgreen500]

Hi,

it appears this was used for the mitral valve. And also that this was originally put in journals in 2003!

http://www.ingentaconnect.com/content/tandf/scar/2003/00000037/00000004/art00012


Chris

 

[Valve-Viking]

I saw an interwiew with the first candidate, a guy in his early fifties, Mr Roger Forslund. He was very happy to contribute to the trial and looked remarkably fresh right after surgery! Very brave man and someone many of us might be very thankful too some years down the line!!

The valve was used in the aortic position for now as far as I could gather.

Will keep you updated.

/
Martin

 

[Andyrdj]

The "20 years equivalent"

The "20 years equivalent"

I've often wondered about the detailed simulation machines they use for this, how good they are at both flow modelling, and the more intricate chemical modelling of the body's calcification of valves - which some doctors regard as a low level immune response.

The big question is: how good are the simulators? How well do they model and duplicate the causes of clotting? How good a guide are they to the human body?

It might affect one's decision to volunteer for such a trial!

 

[medtronic of borg]

All I can say is....

All I can say is....

About time!!!!!! YES!!!!!

 

[ddarsch]

To valve viking

To valve viking

As a two time porcine mitral valve recipient (1991 at age 34) and (2003 at age 48) I have great interest. Is there anything written about the new valve in engish?

 

[Valve-Viking]

I have not seen any information in English regretfully. But I will
post any news here. There are 4 more human replacals due with this
new valve due within the coming months.

Let´s hope the trials goes well, both for the candidates and for the
rest of us.....

/
Martin

 

[Pleasure-to-behold@J]

Interested in following up with this new valve

Interested in following up with this new valve

I would love to hear when and if this new valve gets FDA approval. I am going in for a mitral valve repair soon, but who knows if I wind up with a replacement? The main problem I would have with a mechanical replacement is the coumadin. It may be many years before this newer valve becomes accessible. Thanks for sharing. Irene

 

[ALCapshaw2]

I would love to hear when and if this new valve gets FDA approval. I am going in for a mitral valve repair soon, but who knows if I wind up with a replacement? The main problem I would have with a mechanical replacement is the coumadin. It may be many years before this newer valve becomes accessible. Thanks for sharing. Irene

There IS and intermediate step. The On-X Valves show lower rates of clot formation and other morbid events than other mechanical valves on the market. On-X has been in use for 10 years in Europe, Africa, and the Pacific and 5 years in the USA. Early data is VERY promising. That is the Valve I have requested for my upcoming Mitral Valve Replacement. FDA has sanctioned studies for Aspirin or Plavix only protocol in Low Risk (aortic) patients and reduced anti-coagulation in Medium Risk patients. See www.onxvalves.com for info and contact info. They have been VERY helpful in sending supporting documentation to me and my doctors.

'AL Capshaw'

 

[Ross]

I would love to hear when and if this new valve gets FDA approval. I am going in for a mitral valve repair soon, but who knows if I wind up with a replacement? The main problem I would have with a mechanical replacement is the coumadin. It may be many years before this newer valve becomes accessible. Thanks for sharing. Irene

Hi Irene and welcome aboard. May I ask what it is you have against Coumadin? Reason I ask is that every new person coming in says the same things and generally, they have been widely misinformed.