INR & Covid & Antibodies

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Unicusp

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The last thread on this topic was over a month ago so I decided to start a new one.

I had my last surgery in Feb 2021 (On-X aortic valve) and I was vaccinated with the Moderna vaccine in March & April.

I tested positive for Covid last month after returning from a nice vacation in St. Lucia. I believe it was contracted in the Atlanta A/P while on layover. Very crowded shuttles between terminals and of course no mask wearing. It was probably the Delta variant too.

It was bad. Lasted 2 weeks and was getting worse moving to the lungs, close to bronchitis and then would have been pneumonia.

After week 1 and it was still progressing, I actively started calling everywhere to try and get monoclonal antibodies. Discovered that they are very difficult to get and reserved mostly for the dying anti-vaxxers and immunocompromised.

Luckily, someone put me on a list due to my recent heart surgery and I got the 4 - shot treatment of Regeneron. It immediately worked and I could feel positive results the next day. I probably would have been hospitalized and who knows final outcome if I did not get it.

While having Covid, I noticed a significant drop in my INR, from my previous average of 2.6 to 2.1 I carefully increased dosage and was able to raise the INR. But as I recovered and after, on the slightly higher dosage, the INR was as high as 3.8

Now, I’m back to my pre-Covid dosing and INR is returning to my target range of 2.0 to 3.0 with yesterday at 2.8

Just thought I’d share that even though you are vaccinated, you can get Covid and it can affect your INR. Ironic that in our family group of 6 people, I was the only one who got it. No more air travel for me for a while. Although I should be totally immune now!

And if you do contract Covid, try to get the antibodies!!
 

Lynn

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Glad you made it through Unicusp, it sounds like an uncomfortable and scary experience. Your post raises some interesting questions; Covid and INR as well as the issue of building adequate immunity. I was also vaccinated shortly after my surgery (less than 3 weeks) and give the s.. kicking my body had just taken I have had some concerns around my ability to build strong immunity. Still glad I’m double vaccinated and will get a booster when offered in the next few months. When the medical scientists have time, hopefully we will see some quality studies that address issues of Covid and the heart disease in a more in-depth way. Cheers.
 

Chuck C

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While having Covid, I noticed a significant drop in my INR, from my previous average of 2.6 to 2.1 I carefully increased dosage and was able to raise the INR. But as I recovered and after, on the slightly higher dosage, the INR was as high as 3.8
Glad that you recovered. The INR data is interesting.

After week 1 and it was still progressing, I actively started calling everywhere to try and get monoclonal antibodies. Discovered that they are very difficult to get and reserved mostly for the dying anti-vaxxers and immunocompromised.
This is really unfortunate that the monoclonal antibodies are in short supply and hard to get. Immunocompromised - yes, they should have priority. It is maddening that the supply is scarce due to the anti-vaxxers, who are filling up the ICUs with their more severe cases. It would seem more fair to let them self treat with ivermectin, as most of them believe it works better than the vaccine, and save the monoclonal antibodies for others.

I have an idea. Why don't we start a misinformation campaign within the anti-vaxx community, informing them that the monoclonal antibodies "permanantly change your DNA" you know, like they claim the vaccine does. This way they will refuse treatment with the antibodies and make more available for others.
 
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Beach77

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Glad you are better Unicusp!!! Sounds very scary!! It is also disheartening to hear, that the monoclonal antibodies treatments are hard to get. I'm getting my booster tomorrow. Take care and thanks for sharing the info!
 

Unicusp

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Glad that you recovered. The INR data is interesting.



This is really unfortunate that the monoclonal antibodies are in short supply and hard to get. Immunocompromised - yes, they should have priority. It is maddening that the supply is scarce due to the anti-vaxxers, who are filling up the ICUs with their more severe cases. It would seem more fair to let them self treat with ivermectin, as most of them believe it works better than the vaccine, and save the monoclonal antibodies for others.

I have an idea. Why don't we start a misinformation campaign within the anti-vaxx community, informing them that the monoclonal antibodies "permanantly change your DNA" you know, like they claim the vaccine does. This way they will refuse treatment with the antibodies and make more available for others.
Thx Chuck and others. I totally agree. I was dumbfounded when I was told this information. When I questioned the logic behind this, some of the nurses agreed and others defended them. I just find it perplexing that someone is unwilling to take a thoroughly tested vaccine but yet is ok to take an even more novel new treatment with far less testing. Just crazy.
And yes, this does result in some otherwise healthy people who took proactive steps to get vaccinated, wear masks, get Covid, and then die because they could not get the antibodies. Not right.
 

pellicle

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While having Covid, I noticed a significant drop in my INR, from my previous average of 2.6 to 2.1 I carefully increased dosage and was able to raise the INR. But as I recovered and after, on the slightly higher dosage, the INR was as high as 3.8
interesting ... what was the time period involved in this?
 

Christyleedh

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My INR was 3.5 on Monday and 4.8 on Thursday, with no known cause for the increase (diet and meds same, no alcohol). The pharmacist at the coumadin clinic said they have noticed some of their patients have an increase in INR with covid. Now I’m wondering if I have covid and don’t know it! (No symptoms).
My numbers have dropped unexpectedly, but this is the first time they have gone up so high so quickly with no apparent cause.
 

sharky7

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Glad that you recovered. The INR data is interesting.



This is really unfortunate that the monoclonal antibodies are in short supply and hard to get. Immunocompromised - yes, they should have priority. It is maddening that the supply is scarce due to the anti-vaxxers, who are filling up the ICUs with their more severe cases. It would seem more fair to let them self treat with ivermectin, as most of them believe it works better than the vaccine, and save the monoclonal antibodies for others.

I have an idea. Why don't we start a misinformation campaign within the anti-vaxx community, informing them that the monoclonal antibodies "permanantly change your DNA" you know, like they claim the vaccine does. This way they will refuse treatment with the antibodies and make more available for others.
your attempt at the BLAME GAME is baseless! lay off of the unvaxed, why dont ya! it is all BS, and cause you and yours dont see that, well that is your problem, and not mine! and although those like you try to make it a problem that I or any others may choose to remain unvaxed, that is our right to decide, and not yours nor anyone else's!!! not now, and not ever! So make all the baseless claims you want to, this is also your right! and BTW, if you choose also to live under a socialist govt, this also is your choice, aint it? so go live somewhere they already have those types of GOVTs, you cannot have the USA, and it is not yours for the taking!!! WOW [AND HELL, if your vaxed anyway, why the hell are you even concerned at all, about anyone else, vaxed or unvaxed? YOUR VAXED and now safe from everyone else, or aint you?
 

Chuck C

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lay off of the unvaxed, why dont ya! it is all BS, and cause you and yours dont see that, well that is your problem, and not mine!
What's all BS? Covid? The vaccine? The fact that the vast majority of critical cases are among the unvaccinated? That the unvaccinated, due to so many of them ending up as severe cases in ICU, are using up the supply of monoclonal antibodies, and filling up the ICU units?

I guess I could link a whole bunch of statistics regarding the % of hospitalized cases and deaths among the unvaccinated compared to the vaccinated, but we both know that you will just disregard it as BS, part of a big conspiracy.

WOW [AND HELL, if your vaxed anyway, why the hell are you even concerned at all, about anyone else, vaxed or unvaxed?
I think we may have an attention span issue here, among other things. Did you even read the original poster's comments? You're creating a straw man argument. There never was a claim that the vaccine is 100% effective and many who got theirs early are now 6 months+ their last dose, and are vulnerable again to having a breakthrough case.
 

Unicusp

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My INR was 3.5 on Monday and 4.8 on Thursday, with no known cause for the increase (diet and meds same, no alcohol). The pharmacist at the coumadin clinic said they have noticed some of their patients have an increase in INR with covid. Now I’m wondering if I have covid and don’t know it! (No symptoms).
My numbers have dropped unexpectedly, but this is the first time they have gone up so high so quickly with no apparent cause.
Interesting. My theory is since Covid affects everyone differently, it also probably results in INR going up in some and going down in others. Covid is very unique. I did not lose taste and smell like others, and don't have the lingering dry cough either. But, I am still more tired than before and fatigue easier. Sleep longer hours now. A friend of mine got Covid a few months back (he was vaccinated with Pfizer) and he still has a bad dry cough. Another fully vaccinated friend had Covid a few months back and now has strange heart issues with irregular heartbeat, palpitations, short of breath etc. and he was very healthy before. It's basically a lottery. Don't know what strain you may contract and how it affects your body.
 

Unicusp

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What's all BS? Covid? The vaccine? The fact that the vast majority of critical cases are among the unvaccinated? That the unvaccinated, due to so many of them ending up as severe cases in ICU, are using up the supply of monoclonal antibodies, and filling up the ICU units?

I guess I could link a whole bunch of statistics regarding the % of hospitalized cases and deaths among the unvaccinated compared to the vaccinated, but we both know that you will just disregard it as BS, part of a big conspiracy.



I think we may have an attention span issue here, among other things. Did you even read the original poster's comments? You're creating a straw man argument. There never was a claim that the vaccine is 100% effective and many who got theirs early are now 6 months+ their last dose, and are vulnerable again to having a breakthrough case.
Well stated. In addition, the Covid vaccine is similar to the Flu vaccine in that it cannot possibly protect against all newer strains. And a very important fact that Sharky7 is missing is that as more people refuse to get vaccinated, it provides Covid the opportunity to mutate which means the current vaccine is no longer effective and needs to be modified. Until Covid is eradicated (if ever) we are probably looking at future annual vaccines.
So ironic that Sharky7 resides in Florida. The land of the unvaccinated, misinformed, and highest death count. Keep listening to and trusting Ron Death Sentence. Carry on!
 

almost_hectic

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Florida. The land of the unvaccinated, misinformed, and highest death count. Keep listening to and trusting Ron Death Sentence. Carry on!
Actually California has the highest number of covid related deaths, just to be clear
 

Chuck C

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Actually California has the highest number of covid related deaths, just to be clear
Well sure, as we have by far the highest population. What is more relevent is the death rate, not the overall death count. California is 35th in death rate. The CA death rate is 182 per 100,000. Florida death rate is 277 per 100,000.

 

Chuck C

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Ok well not what you said so... in which case Florida is still not the highest. That would be Mississippi
To be clear, you're confusing me with someone else. I never said that Florida had the highest death count, nor did I say that it had the highest death rate.

But, in fairness to the person who did, it really depends on which time period we are talking about. Florida at various times has led the nation in new cases, number of deaths and death rate:

 
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Unicusp

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To be clear, you're confusing me with someone else. I never said that Florida had the highest death count, nor did I say that it had the highest death rate.

But, in fairness to the person who did, it really depends on which time period we are talking about. Florida at various times has led the nation in new cases, number of deaths and death rate:

Exactly. I recall hearing it but do not follow the latest. It's just ridiculous that this is even being discussed or debated. Oh well.
 

almost_hectic

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Exactly, because in the end it changes nothing... and personally I wasn't debating anything. Just pointing out the facts. Seems often when people like to Florida bash they don't always know the whole truth. Often people just like to repeat what they hear others say and then lump ALL of us together as the bad guys down here and the cause of everyone else's problems.
 
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carolinemc

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What a so called nurse said that has no facts to back up the claim of how a person's high Protime. even stress and non activity and elevate the protime numbers.
 
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