Anyone else hear about this?

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J

jtbass

I was on my way to work today and heard a nationally syndicated health talk show ( vitamin and supplement enthusiasts) talking about a new study that recommends that warfarin users should take a vitamin k supplement.
I hope that Mr. Lodwick will have a response, but isn't this giving out bad info on a national level?
Could I missing something?

Here is the gist of what they presented on their website:

"Animals given high levels of vitamin K showed a 37 percent reduction in calcium buildup in their arteries, a new study finds.

Arterial calcification is an independent risk factor for cardiovascular disease, researchers noted.

The Dutch study, by researchers at Maastricht University, is the first in animals to show that arterial calcification and resulting decreased arterial elasticity can be reversed by consuming high levels of vitamin K. The findings support the results of a Rotterdam population-based study published in 2004.

This research into the benefits of high vitamin K intake may prove especially important for people taking blood thinning medications, such as warfarin, which are known to cause rapid calcification in the arteries. Many patients taking blood thinners aren't aware of this risk, the researchers said."

Just wanted to post this and see if anyone else heard this....I regularly consume vitamin k veggies, but do it on a regular basis like recommended on the warfarininfo website- no lettuce binging!
:confused:
 
Very interesting. TY for the info. Curious to see what Al will add.

BTW, just returned from Ocean Hammock. Palm Coast is a beautiful place! Was surprised to see how "downhill" Daytona had gone! Many years since I had been there. Maybe it's just looking bad from the hurricane aftermath? Was surprised to see buildings on the beach still in shambles.
 
Al has posted about a study/studies that have shown that warfarin users that take a regular amount of K have more stable INR's. I'm sure if you did a search you could find it.
 
Somewhere in my internet travels I came across a European study on the INR control success rate with a combination warfarin and Vit K medication. Though the warfarin levels were higher, those with the Vit K had better control than those on just regular diet and warfarin. Makes sense to those of us taking the rat poison. Couldn't find the site with a search today, just too many hits to sort through. Maybe the + effects of Vit K on other systems other than clotting are not blocked by the warfarin. For me, I just eat what I like (had a spinach salad yesterday) take my pills, and tweak things a bit if I get too low (getting it down is easier than getting it up).

On re-read...that could be read in an alternate way :eek: - the INR I'm talking about :D

Hey, just noticed...almost 2 years since my big day!
 
Jeff

Jeff

Congrats on your up-coming ann. of VR.2 years. I ,too, eat what I want. I agree, too, getting it down is easier than getting it up..:D why I am glad mine (INR) always stays above 3.0...Bonnie
 
I take Walgreens Super Aytinal multivitamins with 80 mcg Vitamin K (approx the RDA for 'normal' folks). Since doing this my INR has been extremely stable - especially since I seem to be quite sensitive to fluctuations from dietary intake of Vit K. Obviously I had to adjust my warfarin level to counteract this amount of Vit K but it's really helped. I couldn't seem to balance my diet - consuming approx the same amount of Vit K in food every week.
 
The argument against this is that the people on this site like RCB and JoAnn etc are the people who have taken warfarin longer than anyone else in the world and they do not have this.
 
vit k

vit k

I only take vitamins and protein bars with NO vitamin K. Reason being, other than my coumadin I don't take anything else daily, just don't think it's necessary.

I could see how titrating coumadin against a consistent daily intake of vit. k from a supplement that is higher than dietary intake could stabilize your INR if your dietary intake is inconsistent.

I've had no major fluctuations w/ my INR, so I'd rather not mess with my current regimen.

Also BTW I take coumadin, not warfarin don't know if that makes a difference. I know they are equivalent, but the FDA does allow greater fluctuations in the amount of active ingredient in generics vs namebrand. Don't mean to open a can of worms with this, but OK too late.

Patty
 
The can has been opened several times. Do a search and you will find it.
 
Coumadin or warfarin ?

Coumadin or warfarin ?

This is a question that I fought with my doctors about for at least the last twenty + years. In the early '80s, pharmacists were suggesting my switching to "generic warfarin". My docs maintained the attitude of "my mind is made up and don't confuse me with the facts" and I stayed on Coumadin. About 2 1/2 years ago I got fed up with paying the inflated price of Coumadin and sought written information (not hearsay) comparing the brand vs generic "warfarin". The FDA sent me info showing the "equivalency" between brand and generic drugs such as warfarin. Both Taro and Barr Labs sent me info showing the equivalency between their generic and Coumadin. I asked Bristol, Meyers Squib for ANY info they had showing their Coumadin to be more consistant, effective or safer than generic warfarin and they could not, or would not, provide any info. I have been on generic warfarin for about two years with no adverse effects and my INR numbers parallel my numbers with Coumadin at the same dosage levels. Coumadin warfarin is a drug that has been on the market for +/- 50 years (I have taken it for almost 40 years) and it continues to carry an inflated price thru misinformation and fear. Incidently, I buy 90 5mg Warfarin for $12 at either Walmart or Kroger. That's a lot less than Coumadin($106 @ Kroger).
 
This is just what should be expected.

Twenty years ago the technology might not have been there to make them exactly the same but it is in common use now.

It is rather telling isn?t it that BMS could not provide any data saying that Coumadin was better
 
wormcan

wormcan

Perhaps that's why my cardio favors coumadin - he's been in the business for a while and perhaps had some bad experiences with early generic formulations. I'll ask him about it next time I'm in for a checkup. The coumadin costs me a lot more $$ than the generic.

The wormcan is now closed :) (for now):D

Patty
 

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