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Noted - thanks!

Thanks, guys. Knew I could count on you. I took 5mg (normally take 8mg) tonight. Will resume 8mg tomorrow night. By the way, Pellicle, I did try running your model tonight to get some insights, but the resolution is 24 hours, and my situation required 12 hour resolution. Didn't take the...

Hi All! Been a while since I've been on the forum - so greetings to my old pen pals. I missed my dose last night and its been so long since that has happened that I forgot the protocol. So I took a full dose this morning. I see that I probably should have just taken a half dose this morning...

Thanks much for all of the informative replies. I learned a few things!

Hi all. My INR recently spiked to 5.2. I couldn't figure out why. Then I remembered that I recently switched out some of my Coumadin with Warfarin because the insurance company no longer covers Coumadin. So I did a little digging and found this article and this FDA publication. I had heard...

Awesome! Every day is a gift and may you have many more such gifts!

I'm speaking from ignorance here, but I think pacemakers are often put in to keep the heart going when it accidentally stops. If your heart is skipping a couple of beats occasionally during the night (if your hear rate is 67 and there is a 3sec pause, then it has skipped two beats), they...

Fantastic - see, it really can happen. Congratulations!

I see you have received some great info and suggestions from this amazing community. Though I ultimately decided to have my AVR locally (DC area) due to the excellent surgeon and facility close to home, I did take time to first visit Cleveland Clinic and evaluate it as an option. Based on my...

Hi Pellicle - that's the spreadsheet I was looking for! Any way I can get it from you again? I think you were the one to originally provide it. Or just tell me the windowing model you use. Thanks, pem

Hi! As some of you may recall, I have to adjust my InRatio2 readings in order to get accurate lab-equivalent values. The formula I use is: Predicted_Lab_Value = InRatio2_Value^X + Y. For me X=0.75 and Y=0.25 based on about 20 side-by-side tests (within an hour of each other, with no food...

Indeed :) Thanks for a thoughtful technical analysis. I think there are different mechanisms at play, as you suggest, regarding the action of various agents on thrombolitic processes. For example, heparin acts in a different way, I think. In my own oversimplified way of thinking about this...

Hi Madsometimes, Thanks for your feedback on this. So glad it worked out for you! From what you wrote it sounds like the ablation was done using a catheter - is that right? If so, do you happen to know if it was venous or by artery? Also, do you think an ablation procedure to treat a-fib...

Hi Kim, Thanks for sharing your experiences. In what way were your results mixed? Have you done anything else to address the mixed results over the last four years, or just lived with them? I think the purpose of this one is to address a-fib, so I wonder if that means it isn't quite so...

Hi Terry, This is great information - thanks. Glad the ablation solved your problem! Best, pem

Thanks pellicle. I understand that, in terms of INR, there was very little difference between the two responses, but I wonder if INR provides is by itself completely predictive of outcome. In other words, perhaps there are effects concerning the fluctuation of coumadin levels that are not...

Fantastic! So glad for the great outcome. Your tissue valve could last considerably longer than 10 years. Apparently they just keep getting better and better. It is kind of exhilarating in a strange sort of way to simultaneously be recovering from the trauma of surgery to having an...

Hi. A family member has a persistent arrhythmia. It might be tachycardia. They tried cardioversion three times. The first two times it didn't stick and the third time it just wouldn't take. So they are recommending ablation. Has anyone had good or bad outcomes with this? Also, how...

Thanks for running the simulation. Now you've got me curious. I might play around with this too! There is still the question of whether a quick return to nominal INR is better or worse (in terms of health outcomes) than a gradual return, even without overshooting. Some studies suggest that...

I do exactly that. And this is a good reminder to refresh my vial (since it is in my pocket all the time, it stays pretty warm and probably loses its "freshness"). If you want a link to vials that work for this, let me know. I think the one I have is waterproof. Best, pem