Nia:
I have shown pedigreed cats since 1989 and am now a shorthair apprentice judge. I carry antibiotics (amoxi) with me to shows and have also had liquid clindamycin. Even the most docile cat can scratch or nip if startled, frightened or threatened. If I approach a cat that seems a little upset, I take a feather or other distracting device to help me in getting it out of the judging cage. Sometimes just talking first very soothingly to the cat helps calm it down. If all else fails, I ask for the handler (owner or agent) to transfer the cat from judging cage to judging table.
We have a prima donna cat at home, a retired award-winning cat, now 11. She's an alpha cat and loves to attack her brother and half sister. We have a couple of spritzer bottles to squirt at her when she gets like that. I do not attempt to handle her or the other two cats when she's like that.
Cats' and dogs' mouths are big sources of bacteria -- as are humans' mouths! If bitten or scratched, always thoroughly wash the site with warm water and antibacterial soap. If there is a puncture wound, immediately start taking amoxi. I take 2,000mg of amoxi immediately, then follow up every 8 hours with 500mg for 24-48 hours. I've never gotten an infection. I'm not sure what the risk of endocarditis would be.
I've been bitten numerous times, once bad enough to send me to my PCP; I was very careless around a male who had just been neutered and was still feeling very hormonal.
Here are several things you can do when you're baby-sitting:
1. Ask the owners where they keep cat treats. If they don't keep cat treats on hand, ask if there's something you can use in place of a cat treat. We keep baby food (lamb, veal, chicken & turkey) as cat treats. Some of our cats adore Fancy Feast, so we'll pop open a little can of that. Sometimes food -- particularly turkey -- will soothe an animal.
2. Ask the owners to trim the cat's claws before you arrive. We trim claws every 7-10 days. I am vehement about short claws on cats now! (Also, if claws grow too long, they can actually impair a cat's ability to walk properly.)
3. By any chance is this a calico or tortoiseshell female? A high percentage of calico (red-black-white or blue-cream-white, i.e., gray-beige-white) or tortoiseshell (red-black splotched or blue-cream splotched, no white) cats have a little unusual personality, sometimes called "tortietude." Think of a cat with low- to high-level PMS...
4. Create some toys for the cat -- wadded-up balls of shiny foil, some paper bags, long strips of fabric (not things like shoelaces), feathers -- and see if the cat will interact positively.
5. If the cat is outright aggressive, rather than not being comfortable around strangers, ask that he/she be kept in a closed room (with litter box, food & water) while you are working at the home.
Let me know how this goes. I can also consult a feline behavior book at home, written by Dr. Bonnie Beaver, a behavior specialist at the Texas A&M Veterinary School.