This stuff probably IS trial and error. It's up to the patient to report issues with medications.
I've had issues with many of the beta blockers.
After my bouts with rhythm issues in March, April and May, my elecrocardiologist switched me to verapamil. He started me on the expensive 180 mg daily extended release dose - very expensive, to 80 mg twice daily - and after this caused dizziness, dropped it to what he calls a minimum dose (he may have said 'baby dose') of 40 mg twice daily (I cut 80 mg pills in half).
My heartrate dropped into the high 30s - maybe not related to the beta blocker -- a pacemaker took care of this -- and my blood pressure is pretty normal.
Back to the original issue - prescribing beta blocker must be trial and error because none are without possible side issues, and it's probably not possible to know, with absolute certainty, how a person will react with a particular beta blocker. If there WAS a beta blocker with no negative effects, wouldn't that be the ONLY one that is, ultimately, available?