This might bring some anticoagulation changes

[pellicle]

Hi

Long-sought mediator of vitamin K recycling discovered

The protein FSP1 inhibits ferroptotic cell death.

www.nature.com

 

[MdaPA]

Can you please share an attachment of this article as it's asking to buy or subscribe to view it (unless that violates any rules)?

 

[Critter]

Too bad costs money to read

 

[pellicle]

Can you please share an attachment of this article as it's asking to buy or subscribe to view it (unless that violates any rules)?

Currently trying to source such, I don't work for the Uni anymore..

 

[ATHENS1964]

I didn't understand much I had never heard of the term Ferroptosis before
If someone could say in a few words what could happen in coagulation.

Ferroptosis: mechanisms, biology, and role in disease

The research field of ferroptosis has been enjoying exponential growth over the past few years, since the term was coined in 2012. This unique modality of cell death, driven by iron-dependent phospholipid peroxidation, is regulated by multiple cellular ...

www.ncbi.nlm.nih.gov

 

[pellicle]

I didn't understand much I had never heard of the term Ferroptosis before
If someone could say in a few words what could happen in coagulation.

Ferroptosis: mechanisms, biology, and role in disease

The research field of ferroptosis has been enjoying exponential growth over the past few years, since the term was coined in 2012. This unique modality of cell death, driven by iron-dependent phospholipid peroxidation, is regulated by multiple cellular ...

www.ncbi.nlm.nih.gov

personally I had not heard of those things before, but my view is that

1. I'm going to learn something by understanding that paper
2. It's likely something novel in anticoagulation will emerge from this
3. its not going to effect what I do and what's available in my life time

If Putin doesn't unleash a horror upon us then it's good research for the the future.

As to ferroptosis, well that wasn't even known when I did my biochem degree ...

 

[Critter]

I have never heard of ferroptosis only apoptosis. Programmed cellular death. If the mechanism doesn’t work well it can lead to cancer, autoimmune diseases, and all sorts of nasty stuff. We are pre-programmed to die, unsettling concept.