Professional Dingbat, Guru and MerkintologistSupporting Member
- Nov 4, 2012
- Queensland, OzTrayLeeYa
Apparently in this worldThey market that they keep their patients within therapeutic range 70% of the time. In what world is it ok to be in range 70% of the time with a mechanical valve?
Time in the Therapeutic Range (TTR): An Overly Simplified Conundrum
Anticoagulation with warfarin has been used for over 60 years; however, its administration is fraught with difficulty since many factors can affect warfarin dosing. The concept of time in therapeutic range (TTR) has become a popular way to report warfarin ...
In the ninth National Conference on Anticoagulant Therapy in 2007, approximately 75% of attendees reported measuring the TTR as a quality indicator for their anticoagulation clinics. However, there was a general unawareness that the method used to measure TTR can affect the results. Approximately 65% used the fraction of INRs in range, 15% relied upon the linear interpolation analysis and 10% employed the cross-section-of-the-files method.6
In recent major clinical trials, the numbers have been higher, with mean and median values often in the mid- to high 60% range.