Would these cause regurgitation/aortic insufficiency. I did not have Stenosis. Would it be a gradual change and take 25 years to begin to fail?Very interesting. Thinking back I took phentermine for a very short time in the 2000’s I believe but it didn’t do anything so I stopped. I never took anything with phen phen. I specifically remember people getting really sick and having crazy side effects and it wasn’t worth it to me. The only think I remember taking at that time was Herbalife and metabolife. So late 90’s. I remember bc I tried to lose weight after my second son was born inn1996.