Agian... I realize that this doesn’t entirely discount your point here, and that I really shouldn’t have to explain this to you because you must understand it, but recent findings have very, very strongly implicated high Lp(a) as a causal factor for the development and accelerated progression of calcific AVS in otherwise normal people. The fact that high Lp(a) is also associated/causative of other heart issues such as CAD strengthens your argument, but this too is maybe less of a “lifestyle” issue and more of a genetic one.Agian;n880871 said:Agreed Superman, but most people that need AVR don't have bicuspid. Poor lifestyle does indeed complicate things.
Most CAD risk factors are 'modifiable'. He did say "... not all people but enough to skew the results towards the negative." That's actually true.
Is lifestyle a factor? Absolutely! But genetically high Lp(a) can kick lifestyle outcomes from getting diagnosed with heart disease in your 60s to getting diagnosed with AVS and CAD in your early 40s. Big difference there.