Daily Aspirin Post Aortic Valve Replacement

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I don't recall whether or not one of my doctors told me to take 81 mg aspirin (he or she may have said 'baby aspirin, which is also 81 mg). Many of us here take the 81 mg enteric coated aspirin.

When you're on warfarin, you don't want anything to add to the anticoagulation effects of warfarin. Aspirin does - using a different mechanism. It makes the platelets less 'sticky,' which can reduce the blood's ability to clot. Its effects, strangely, can't be detected by our INR meters.

I broke a wrist a few years ago. I told the doctor that I was taking an NSAID for the pain. He didn't like this - he told me that the NSAID can effect clotting and that I shouldn't take it when I take warfarin.

So - I take the 81 mg aspirin at night, once a day. If I have a lot of pain, I'll occasionally have a generic ibuprofen or two - but only when the pain is severe.

The reasoning for the 81 mg enteric coated aspirin -- it's supposed to help in some way (reduce risk of heart attack?), and it doesn't seem to have any negative effects. With no negative effects, if it can be of any value, why NOT take it? And, FWIW, if its effects are lower because it dissolves in the intestines, that may make it slightly safer than a pill that explodes in the stomach.
 
My native valve was repaired via valvuloplasty and I have been on daily full strength 325 mg aspirin for 17 years now with no ill effects. I've taken both enteric and regular, and I don't notice a difference. I don't take warfarin or any other cardiac prescribed medicines. If I am getting this right, it was prescribed because I have increased risk of developing a-fib due to all the turbulence from my still quite wonky valve that increases the chance of developing a clot / stroke. Also they put a hole in the septum of my heart during the repair which also increases stroke risk.
 
My native valve was repaired via valvuloplasty and I have been on daily full strength 325 mg aspirin for 17 years now with no ill effects. I've taken both enteric and regular, and I don't notice a difference. I don't take warfarin or any other cardiac prescribed medicines. If I am getting this right, it was prescribed because I have increased risk of developing a-fib due to all the turbulence from my still quite wonky valve that increases the chance of developing a clot / stroke. Also they put a hole in the septum of my heart during the repair which also increases stroke risk.
325 mg a day for 17 years!
That is impressive ... and very reassuring. Especially the “... no ill effects”. Thank you @dornole 🙂
 
Hi @Seaton - sorry to hear they are prescribing you Omeprazole long term. I'm sure I have read recently that this, and other Proton Pump Inhibitors, are being advised to be prescribed only short term as long term they have many side effects. They interfere with vitamin B12 production, interfer with calcium and other mineral absorbtion (the problem with calcim absorbtion can lead to osteoporosis), also the PPI can lead to lower gastrointestinal problems due to incomplete digestion and due to overgrowth of bacteria in the small bowel and more - this is because the Proton Pump Inhibitor stops the production of stomach acid. We do need our stomach acid, it's not there by mistake, it is vital for our digestion in the stomach.

An enteric coated low dose aspirin would be much better, or better still no aspirin and some other alternative.

What is the reason for the permanent aspirin ?

As you know, I have a bioprosthetic valve, but I have never been prescribed aspirin post surgery. The reason I know about Proton Pump Inhibitors is that I was prescribed them a few years ago because of another med I was being prescribed and looked into them and looked into why we need stomach acid - I refused to take them.

I can see you are in a difficult situation :(

I was on PPIs for years then read the reports on potential leading to Alzheimers and worked my way off. Many doctors over prescribed them as it was always supposed to be a short term drug not a long term one. Now I watch what I eat that can upset me stomach and if I know something will upset it I take Pepcid or something like that 30 minutes before I eat. Also my GI years ago suggested raising the head of the bed 3-6 inches to help prevent reflux while sleeping. We do about 2.5 inches and now when we sleep on a level bed is is weird.
 
I've been taking the "standard" 81 mg enteric coated aspirin (cheapest generic) for over 10 years. I also take an H2 receptor blocker for acid reflux/excess acid production. For several years I used various PPI's, but then moved away from then when the issues of longer term use surfaced. I then switched to Zantac (ranitidine) for many years. The ranitidine was effective and very well tolerated. . . until last month when they announced that something in it was a carcinogen and they took it all off the store shelves. I am now trying famotidine, 10 mg morning and night. The jury is still out, but it seems OK.

We believe my acid issues were there before I started the aspirin, so I doubt that the aspirin has been any sort of issue for me.
 
As you know I had AVR 2 weeks ago , my surgeon that study in US and worked at Cleveland and Texas thoracic hospital said the guidelines is aspirin + (walfarin -cumadin ea) . He give me ezomeprosol for protection .
 
I currently take a daily 75mg dispersible aspirin (in water) following a capsule of omeprazole (to aid the stomach for the aspirin ingestion). The aspirin is now a permanent med for me post AVR, as prescribed by my surgeon.

I’ve been on the omeprazole for some weeks now and I feel it is upsetting my stomach. Stomach upset is one of its side effects. Other side effects of omeprazole, especially on long term use, don’t look that attractive.

I skipped my omeprazole this morning to see if my stomach settles and just took the aspirin. I spoke with my GP later and she suggested I switch to lansoprazole for a month or so and see how I do with that. Lansoprazole is in the same ball park as omeprazole in terms of side effects pretty much.

I’d rather not be taking one of these proton pump inhibitors with my aspirin. But the consensus seems to be it aids the safe ingestion of aspirin by reducing the risks of internal bleeds from prolonged aspirin prescription.

My questions:
Are others here with bioprosthetic valves on daily aspirin combined with any of these stomach protective meds?​
If so, have you experienced any side effects as the weeks pass?​
Or are you taking aspirin alone?​
If just taking aspirin (long term), have you experienced any physical issues ... bleeds etc.?​
Or is everything hunky dory?​
Thanks in advance!
Hi
I had Edwards valve 3 weeks ago and am now taking lansoprazole 30 mins before breakfast, aspirin + Bisoprolol with breakfast and Atorvarstatin before bed.
I don't think I'm experiencing any particular side effects.
 
Hi
I had Edwards valve 3 weeks ago and am now taking lansoprazole 30 mins before breakfast, aspirin + Bisoprolol with breakfast and Atorvarstatin before bed.
I don't think I'm experiencing any particular side effects.
Hey @Stevebav, great to hear you’ve finally had your AVR! Hope all going well for you post surgery and things healing nicely.

I’m glad no issues showing up with your meds.

All seems steady for me on just aspirin currently. Have my first post-op annual (phone!) consultation with a cardiologist in September, so will discuss and review my meds then. I’m assuming the consultant will say continue with the aspirin but I’ll bring up the fact I don’t take any PPIs with it and see what his response is.

Very best to you as your recovery progresses.
 
I currently take a daily 75mg dispersible aspirin (in water) following a capsule of omeprazole (to aid the stomach for the aspirin ingestion). The aspirin is now a permanent med for me post AVR, as prescribed by my surgeon.

I’ve been on the omeprazole for some weeks now and I feel it is upsetting my stomach. Stomach upset is one of its side effects. Other side effects of omeprazole, especially on long term use, don’t look that attractive.

I skipped my omeprazole this morning to see if my stomach settles and just took the aspirin. I spoke with my GP later and she suggested I switch to lansoprazole for a month or so and see how I do with that. Lansoprazole is in the same ball park as omeprazole in terms of side effects pretty much.

I’d rather not be taking one of these proton pump inhibitors with my aspirin. But the consensus seems to be it aids the safe ingestion of aspirin by reducing the risks of internal bleeds from prolonged aspirin prescription.

My questions:
Are others here with bioprosthetic valves on daily aspirin combined with any of these stomach protective meds?​
If so, have you experienced any side effects as the weeks pass?​
Or are you taking aspirin alone?​
If just taking aspirin (long term), have you experienced any physical issues ... bleeds etc.?​
Or is everything hunky dory?​
Thanks in advance!
My doctor has me on baby aspirin since my eye stroke three years ago. No problems. Was of the aspirin for several years after my other cardio took me off the regiment. They had found it caused excess bleeding. But I was without for three months of taking my Warfarin, the doctors thinks that was the cause, but I am also diabetic, who are also apt to have eye strokes. It is common but uncommon. Stranger as it is. I was lucky.
 
Hey @Stevebav, great to hear you’ve finally had your AVR! Hope all going well for you post surgery and things healing nicely.

I’m glad no issues showing up with your meds.

All seems steady for me on just aspirin currently. Have my first post-op annual (phone!) consultation with a cardiologist in September, so will discuss and review my meds then. I’m assuming the consultant will say continue with the aspirin but I’ll bring up the fact I don’t take any PPIs with it and see what his response is.

Very best to you as your recovery progresses.
Hi
Pleased to see you are doing OK - allbeit after some bumps in the recovery road.
all the best to you too.
 

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