Not nearly enough. Check my graph (from the blog post) again carefully. Remember graphs are not just pictures they

**are** the numbers ... (sorry if you were already thinking that way, but many seem to forget it after primary school)

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So, my graph is a little complex, as you can see it has two Y-axes (one for INR, the other for dose in mg because its presenting two entirely different things together in a relationship). I explain that in the post. Quoting from that blog post:

*My process was this:*
*measure INR daily (in the AM, usually about 8am)*
*my usual dose time is 7pm*
*I charted INR and dose*
*the graph below has INR on the LHS Y axis and dose in mg on the right axis*
*the bars represent actual data and the lines part of my model*
*my colonoscopy was Wednesday*

So reading across (left to right) you can see that I had my last dose on Saturday (don't ask me why I did the half dose rather than just go off.

As I expected (from recording previous situations) it took until Wednesday (the exact day of the colonoscopy) to reach the agreed INR.

I then took 9mg (which7mg +30% extra) and observed that it was not coming up at a good rate (not unexpected, but one has to do the experiment right?) and so on Friday I took 12mg (or nearly 80% more). I then took 8mg until the following Wed when (being concerned about a possible overshoot {

*see the magenta ellipse*}) I reduced back to my normal dose and then managed "normally".

So, as

@Keithl has suggested double doses in the first two or maybe 3 days would get you there faster. Plinking around with an increase of 10% is like putting a cup of water into the bath to raise the level.

This graph shows an estimation of the "load" of warfarin that accumulates in your body as a result of resuming taking dose of 5mg

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it takes about 6 days to get to steady state (its theory right, practice will be slightly different), and so the INR will lag behind that by one or two days.

Now if you take double the dose in the first two days you will see this

View attachment 887853
where the accumulation load will get there faster and then roll off to the "steady state (follow along the blue line for dose right

.

To me its uncertain what sort of INR effect this will have, so myself I'd be inclined to do with a staged double, then decreasing

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anyone have any thoughts on the above?