For "me" it was very hard to accept the fact i was born with a defective heart; and even harder to accept that "for me" the only repair worth doing was the one that implies taking a pill for life
And, no matter how much tavi talk goes around, i can not prevent thinking like a mathematical engineer; so here is the question: You place a screw with a nut, the screw goes bad and needs to be changed, 2 options, remove nut and screw or pull out the screw and place a nut "inside" the first nut, of course this will be smaller and the screw thinner...., and so on and so forth....
Now, engineering-mathematical question: How many nuts can you insert inside the first nut always sitting there ?
Can you be 100% the "first" nut will last for ever and accept the second one ?
Doctors are not engineers, hardly comprehend high calculus; so they are told what
they are told by BIG Pharma, simple.
For me, this Tissue valve with the TAVI rethoric; DOES have a place , but it is not the sweet blue pill
A plumber would also say with the sealing what happens to how much teflon is between the nut and there is no rotation there is an anchoring system.