Lp(a) is a CAUSAL factor for calcific AVS. Mine is about 13 times normal due to having a pair of mutant alleles in my genome at rs10455872. Do you know your Lp(a)? If you have AVS, then you should, because high Lp(a) is also causal for coronary artery disease and treatments to lower it should be available in the next few years (diet and exercise do not really affect it).
Elevated Lp(a) levels and corresponding genotypes were associated with increased risk of AVS in the general population, with levels >90 mg/dl predicting a threefold increased risk.
Lipoprotein(a) and Oxidized Phospholipids Promote Valve Calcification in Patients With Aortic Stenosis - PubMed
In patients with AS, Lp(a) and OxPL drive valve calcification and disease progression. These findings suggest lowering Lp(a) or inactivating OxPL may slow AS progression and provide a rationale for clinical trials to test this hypothesis.
To reveal this inherited risk for premature heart disease, atherosclerosis, thrombosis and stroke; educate and empower patients and save lives.