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  1. pellicle

    Warfarin Protocol Initiated!

    the model would predict somewhere between 1.8 ~ 2.1 my bet is placed.
  2. pellicle

    Warfarin Protocol Initiated!

    I fixed your graphic 4 weeks a bunch of measurements few alterations in dose with evaluation of that data sadly its what I've come to expect ... they'll blame it on something else ... or say something inane like "why won't your INR go up" ... try the dose lever honey... Sigh Thanks for...
  3. pellicle

    Alternative to Warfarin

    Hi interesting, what sort of drop are we talking? indeed, although the time scales and the amounts may vary. Not knowing "by how much" and "in which direction" you see a change I can't say more. However there are some interesting findings emerging on just where our vitamin K can come from...
  4. pellicle

    Hair color changed after surgery?

    ←_←
  5. pellicle

    Endocarditis Quiz

    "Are you prepared to identify and treat IE in patients?" I don't feel I am ...
  6. pellicle

    How to Choose

    brave and honest ... hats off to you.
  7. pellicle

    Alternative to Warfarin

    and we'll be doing everything by TAVI and they'll last for 50 years... the other one plays Jingle Bells
  8. pellicle

    Alternative to Warfarin

    that's how it is for me, but I can't speak for others.
  9. pellicle

    New Old Member

    discussion on this thread https://www.valvereplacement.org/threads/where-are-you-getting-your-supplies.889453/page-3#post-932793 shows that many in the US are now using Reliaston, although on the West Coast I believe @Chuck C uses some other place well basically you need to adjust your dose...
  10. pellicle

    Emergency Information on phone

    metoprolol ... its the best lol
  11. pellicle

    Emergency Information on phone

    myself I have none of that ... I just rely on doing my best to not have an accident relying on the ER process I know deeply that at my age any accident bad enough where I'm unconscious will be bad news. Best Wishes
  12. pellicle

    Where are you getting your supplies?

    or a failure to tune the ISI for the test reagent properly ...
  13. pellicle

    Where are you getting your supplies?

    well firstly I'm going to say "go with the Roche"; secondly I'm going to say "that lab seems like its a problem".
  14. pellicle

    Alternative to Warfarin

    applause for your Dr ... as one of the sayings goes here "dose the diet, do not diet the dose" Best Wishes
  15. pellicle

    Alternative to Warfarin

    can you provide some links supporting this please? I thought they were basically the same. Its not hard to manage warfarin ... unless you're a clinic.
  16. pellicle

    Alternative to Warfarin

    so: short answer: NO and probably not in your lifetime. Warfarin has very few adverse effects, of which I believe that all of the NOAC's share ... but worse, without the benefits warfarin bring. effectiveness at the desired purpose ability to measure its effect cost effectiveness The only...
  17. pellicle

    Alternative to Warfarin

    actually I don't think even the purpose they are intended for they are very fit for purpose. However with 'stroke' patients the aetiology of the stroke is frequently unknown; so for all we know the drug is "effective" because they never had another stroke event for the drug to have worked on...
  18. pellicle

    Alternative to Warfarin

    But as valve patients are by no means the majority of target patients I can't be sure that such anticoagulants will be approved for us let alone " for patients with mechanical heart disease "
  19. pellicle

    Alternative to Warfarin

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5310120/ We identified 109 eligible studies: 35 for dabigatran, 50 for rivaroxaban, 11 for apixaban, and 13 for edoxaban. The performance of standard anticoagulation tests varied across DOACs and reagents; most assays, showed insufficient correlation...
  20. pellicle

    How to Choose

    something I found a good reflection
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