Nocturne
Well-known member
Unfortunate report on the (apparent lack of) TAVR valve durability:
http://www.medpagetoday.com/Cardiology/PCI/62310
http://www.medpagetoday.com/Cardiology/PCI/62310
Nocturne;n871578 said:Unfortunate report on the (apparent lack of) TAVR valve durability:
http://www.medpagetoday.com/Cardiology/PCI/62310
Superman;n871585 said:I wish they would it more clear who actually participated in the study. At least in the U.S. at that time, most of the patients being approved for that procedure were older and typically not cleared for open heart due to other risk factors.
cldlhd;n871587 said:This is only my personal opinion but for anyone of a somewhat younger age if you're having your valve replaced and durability is your main concern then you should get a mechanical valve. I understand if calcification is a big concern and you believe warfarin may accelerate that process then you have to pick your poison. Unfortunately there is no perfect answer at this point in time.
You can't reverse calcification. Plaques are 20% Calcium. So, a 60% stenosis could theoretically become a 12% stenosis, because it is the lipid content only that can be reversed. CAC scores don't reverse, but can be slowed. Calcium reflects 'mature plaque'; these contribute to angina. It is soft plaques that have the thin caps. These rupture and become susceptible to the clots which cause occlusion. This equates to dead heart muscle downstream.cldlhd;n871592 said:to slow or possibly reverse calcification. Whether or not they come up with that valve that hits all the sweet spots by the time you need it is out of your control.
Warrick;n871596 said:The way the "report" reads to me is that TAVI is doing what it says on the box, and that it's for high risk patients who wouldn't otherwise survive OHS and have a limited life span...
no surprises there...
Agian;n871602 said:You can't reverse calcification. Plaques are 20% Calcium. So, a 60% stenosis could theoretically become a 12% stenosis, because it is the lipid content only that can be reversed. CAC scores don't reverse, but can be slowed. Calcium reflects 'mature plaque'; these contribute to angina. It is soft plaques that have the thin caps. These rupture and become susceptible to the clots which cause occlusion. This equates to dead heart muscle downstream.
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