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Help! INR is 6.4

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  • Help! INR is 6.4

    Hi all!
    My hubby just took his inr test and it is 6.4
    He just had a tooth pulled about 2 weeks ago and the antibiotics gave him such diarreha that he finally stopped taking them. Now tonite he tested his INR and it is really high at 6.4. Should I call the doctor or go to the ER?
    I am starting to panic.
    thanks!

  • #2
    More information may be needed.
    Example:
    When was his last dose of antibiotics?
    What is the dosage of warfarin is he on?
    What is his range?

    Try not to panic - skip a dose. There is a good possibility that the antibiotics have raised his INR - providing the antibiotics have been recently stopped.

    Sorry this is all I can offer and try to retest in 3 days.
    Laughter is the Best Medicine
    MVR March 30/07 Carbomedics Valve - Said and done in 5 days in Canada

    Comment


    • #3
      Chris, has he already taken today's dose?
      BAV-Aortic Stenosis...AVR Oct 11, 2005 / St.Jude Regent mechanical 21mm
      INR Home testing since 2007 with Coaguchek XS...Self-Dosing

      "Caution: I may have been in contact with Nuts"

      Comment


      • #4
        I'm trying to find a thread for you from someone recently whose INR was even higher...I'll let you know if I find it.
        #1 OHS 1980 Wolfe Parkinson White, Duke, Dr Sealy.
        #2 4/08 Tricuspid Replacement (31mm St. Judes Biocor), ASD closure with Bovine Patch, modified right sided Maze Procedure, Mayo clinic

        Comment


        • #5
          here is a link I just found, hope it helps.

          http://wiki.answers.com/Q/Is_it_dang...should_be_done
          Scott
          Mini-AVR (On-X mechanical Valve) 2/29/2008
          Cleveland Clinic
          Dr Gosta Pettersson

          Comment


          • #6
            You could call your local ER or on-call doctor and see what they say. Skip the Coumadin for today.
            Make sure he has no blood in his urine or bowel movements-for tonight anyway,
            and feed him some high Vitamin K foods....cooked spinach, etc.
            BAV-Aortic Stenosis...AVR Oct 11, 2005 / St.Jude Regent mechanical 21mm
            INR Home testing since 2007 with Coaguchek XS...Self-Dosing

            "Caution: I may have been in contact with Nuts"

            Comment


            • #7
              I would retest. If I got another INR in that range, I would call my doc for advice. He would probably tell me to go to ER to knock INR back in range. I am conservative in dealing with warfarin.
              Starr-Edwards mechanical AVR 1967 at age 31.....University of Kentucky Med. Ctr., Drs. Richard Wood & Gordon Danielson surgeons. No surgery (heart or otherwise) since. On Warfarin ACT since surgery with no diet, lifestyle, or activity restrictions....and I live one day at a time.

              Comment


              • #8
                Here is that thread I was thinking about:

                http://www.valvereplacement.com/foru...ad.php?t=27284

                Kim
                #1 OHS 1980 Wolfe Parkinson White, Duke, Dr Sealy.
                #2 4/08 Tricuspid Replacement (31mm St. Judes Biocor), ASD closure with Bovine Patch, modified right sided Maze Procedure, Mayo clinic

                Comment


                • #9
                  NOTE: it takes about 48 hours for antibiotics to get out of your system.
                  Laughter is the Best Medicine
                  MVR March 30/07 Carbomedics Valve - Said and done in 5 days in Canada

                  Comment


                  • #10
                    Good point, Dick. Maybe Chris can test on herself and make sure the reading is about 1.0
                    BAV-Aortic Stenosis...AVR Oct 11, 2005 / St.Jude Regent mechanical 21mm
                    INR Home testing since 2007 with Coaguchek XS...Self-Dosing

                    "Caution: I may have been in contact with Nuts"

                    Comment


                    • #11
                      thanks guys!
                      He did not take todays dose - he tested first - he takes his meds before bedtime.
                      He stopped the antibiotics (clindamycin) about 5 days ago - but still has diarehha!
                      He alternates a 7.5 mg and a 10 mg of coumadin - so every other day is a 7.5.

                      Comment


                      • #12
                        Chris,

                        You have to do what you and Gary feel is most comfortable for you. Definitely test again to make sure. I have been this high and was fine.

                        If the INR is still high, skip today's dose. I would take 1/2 dose tomorrow and then test again the next day before taking the coumadin and see where things are. With taking 7.5/day, he should drop fairly quickly.

                        However, that is just me and I am not a doctor. You might be best at least calling your doctor to get some guidance.

                        Comment


                        • #13
                          Chris,

                          Clindamycin is a powerful antibiotic. The fact that Gary still has diarrhea is a reminder of that. As long as he has diarrhea, his body cannot produce the natural vitamin K in his intestinal tract, and his INR will remain high. The 1st thing you have to do is slow down his gut, and get things performing normally.

                          6.4 isn't panic time, but it is time to cut back. Skipping today is alright. Maybe 1/2 his dose tomorrow. Then resume. Test tomorrow or Saturday to see where the INR is.

                          Getting the diarrhea under control is paramount though.
                          Kristy S.
                          AVR 6-19-01 (S.J. Mechanical)
                          Centura Porter Hospital
                          Dr. Brad Hofer (Surgeon)

                          Comment


                          • #14
                            Getting advice from geebee (and everyone else) is usually pretty good darn advice
                            Laughter is the Best Medicine
                            MVR March 30/07 Carbomedics Valve - Said and done in 5 days in Canada

                            Comment


                            • #15
                              I believe it was Blanche who recently posted about her hubby having a similar INR along with his diarrhea.
                              You could dig out her thread on it.
                              I would also skip today's dose and take half tomorrow, then half on Saturday--if needed and according to what your doc recommends.
                              Don't forget the spinach omelet for breakfast :-)
                              BAV-Aortic Stenosis...AVR Oct 11, 2005 / St.Jude Regent mechanical 21mm
                              INR Home testing since 2007 with Coaguchek XS...Self-Dosing

                              "Caution: I may have been in contact with Nuts"

                              Comment

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